FRIDAY, Sept. 4, 2020 (HealthDay Information)
Individuals with lupus usually are not at increased possibility of hospitalization from COVID-19 due to steroidal medications they acquire to lessen immune system action, a new review finds.
And a similar review discovered that persons with inflammatory kinds of arthritis — these types of as rheumatoid arthritis — usually are not a lot more very likely to be hospitalized with COVID-19 than persons without having arthritis.
Both studies had been led by scientists at NYU Grossman University of Medicine, in New York Metropolis.
The results “should reassure most people, specifically individuals on immunosuppressant therapy, that they are at no better possibility of obtaining to be admitted to clinic from COVID-19 than other lupus or arthritis people,” Dr. Ruth Fernandez-Ruiz, co-author of the studies, stated in an NYU Langone information release.
“Individuals with lupus or inflammatory arthritis have the same possibility factors for acquiring very seriously sick from COVID-19 as persons without having these ailments,” stated Fernandez-Ruiz, a postdoctoral fellow in rheumatology.
Lupus and circumstances like rheumatoid arthritis, psoriatic arthritis and spondyloarthritis are autoimmune conditions in which the immune system mistakenly assaults a person’s have tissues. This brings about inflammation in the joints, pores and skin, kidneys and other parts of the body.
The scientists discovered that lupus people having immune-suppressing medications — these types of as mycophenolate mofetil (CellCept) and azathioprine (Imuran) — had no better possibility of hospitalization (fifteen out of 24) than lupus people not applying the medications (9 of seventeen).
In addition, the COVID-19 hospitalization level for persons with inflammatory arthritis (26%) was related to that of New York Metropolis citizens in general (twenty five%).
An additional acquiring was that people having biologic drugs for arthritis, these types of as adalimumab (Humira) and etanercept (Enbrel), or the antiviral hydroxychloroquine, had no better or decrease possibility of COVID-19 hospitalization than individuals not having the drugs.
But people who took steroids identified as glucocorticoids, even in delicate doses, had a ten situations higher possibility of COVID-19 hospitalization than individuals who did not acquire steroids. Even though the acquiring is statistically sizeable, the study’s tiny dimensions may well overestimate the precise possibility, the scientists pointed out.
The studies had been not long ago released on line in the journal Arthritis and Rheumatology.
— Robert Preidt
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Resource: NYU Langone, information release, Aug. twenty five, 2020