Autosomal dominant partial epilepsy with auditory features (ADPEAF) is an unusual variety of epilepsy that operates in households. This ailment leads to seizures commonly characterised by audio-relevant (auditory) indicators these as buzzing, buzzing, or ringing. Some people knowledge far more sophisticated seems during a seizure, these as unique voices or audio, or adjustments in the quantity of seems. Some people with ADPEAF suddenly develop into not able to understand language in advance of shedding consciousness during a seizure. This inability to understand speech is recognised as receptive aphasia. Much less generally, seizures may possibly result in visual hallucinations, a disturbance in the sense of smell, a emotion of dizziness or spinning (vertigo), or other indicators affecting the senses.
Seizures associated with ADPEAF commonly start off in adolescence or younger adulthood. They may possibly be activated by unique seems, these as a ringing telephone or speech, but in most situations the seizures do not have any regarded triggers. In most influenced people, seizures are infrequent and proficiently controlled with medicine.
Most people with ADPEAF have seizures explained as straightforward , which do not result in a reduction of consciousness. These seizures are imagined to start off in a section of the brain called the lateral temporal lobe. In some people, seizure activity may possibly spread from the lateral temporal lobe to have an affect on other areas of the brain. If seizure activity spreads to have an affect on the whole brain, it leads to a reduction of consciousness, muscle stiffening, and rhythmic jerking. Episodes that start off as partial seizures and spread all through the brain are recognised as secondarily generalized seizures.